WASHINGTON—The White House reimposed sanctions on Iran, targeting the country’s struggling economy as it seeks to pressure Tehran’s leaders to stop supporting Middle East militant groups and end enrichment of uranium, U.S. officials said.

While President Trump—whose measures reflect the broadest economic action he has taken against Tehran since saying in May that the U.S. would withdraw from the 2015 Iran nuclear accord—has said he is willing to meet with President Hassan Rouhani to see if they can strike a more comprehensive…



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